The Discussion Of Osteoarthritis And Rheumatoid Arthritis

The Discussion Of Osteoarthritis And Rheumatoid Arthritis

Discussion

Both osteoarthritis and rheumatoid arthritis present with several of the same manifestations, such as joint pain and stiffness. How do the two disorders differ?

Rheumatoid arthritis and osteoarthritis are both diseases of joints, but the etiologies are very different. According to Mohammed et al. (2020), rheumatoid arthritis is an autoimmune disease whereby the immune system of the body attacks joint tissues.  When the immune systems attack the joints, it causes inflammation that causes thickening of tissues lining the joint.  This leads to pain and swelling around and in joints, resulting in permanent disability. On the other hand, osteoarthritis is a disease believed to occur due to wear and tear on joints over time. Mohammed et al. (2020) indicate that as a degenerative disease of the joints, osteoarthritis occurs when the cushion/ cartilage breaks down causing stiffness, swelling, and pain. Osteoarthritis and rheumatoid arthritis vary on the most affected joints. Osteoarthritis often affects weight-bearing joints, like hips and knees, and is usually asymmetrical. Rheumatoid arthritis usually affects small joints of the feet and hands and is commonly symmetrical The Discussion Of Osteoarthritis And Rheumatoid Arthritis .

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The pathophysiology of osteogenesis imperfecta and the associated risk factors

A child born with osteogenesis imperfecta is at risk for pathological fracture. Osteogenesis imperfects is a genetic disorder typified by numerous clinical features including brittle bones, low bone mass, and bone deformities. Etich et al.  (20220) posit that the most common cause of this disorder is the heterozygous mutations in collagen genes: COL1A2 and COL1A1. The two different pathophysiologies include: loss of function mutations such as stop mutations result in haploinsufficiency.  Patients have a less than normal amount of collagen, although the collagen is of normal quality.

Etich et al. (2020) posit that other mutations, mostly glycine substitutions, cause modifications of the extracellular matrix because the collagen molecules and subsequent fibles are not able to assemble appropriately.  In addition, the inadequate stability and qualitative disturbance of the bone collagen fuel resorption of bones, because the body attempts to break down the bone that has been disturbed. Heredity is the risk factor for osteogenesis imperfecta. The disorder occurs due to a mutation of genes, which might be sporadic or a child might inherit the gene from one or both parents. Most people with osteogenesis imperfecta have the disease-causing mutation in one of the two genes responsible for coding for the collagen type 1 alpha chain.

References

Etich, J., Leßmeier, L., Rehberg, M., Sill, H., Zaucke, F.., Netzer, C., & Semler, O. (2020).  Osteogenesis imperfecta—pathophysiology and therapeutic options.  Molecular and Cellular Pediatrics, 7, 9. doi: 10.1186/s40348-020-00101-9

Mohammed, A., Alshamarri, T., Adeyeye, T., Lazariu, V., McNutt, L., & Carpenter, D. O. (2020). A comparison of risk factors for osteo- and rheumatoid arthritis using NHANES data. Preventive Medicine Reports, 20, 101242. doi: 10.1016/j.pmedr.2020.101242

Discussion Forum Sample

Discussion questions in NUR-631 are presented with a range of options.

Read the questions carefully and follow directions regarding whether to select one, two or answer multiple questions for the response. Present responses using the sample format provided below and include at least two citations from peer-reviewed journals published within the last 5 years or from the textbooks. References must be in proper APA format. A substantive responses must be at least 150 words in length and pertain to the topic as it relates to pathophysiology The Discussion Of Osteoarthritis And Rheumatoid Arthritis .

Sample DQ

Select one of the following discussion questions for your discussion response.

1. What did Mark Twain mean when he said, “the difference between the right word and the almost right word is the difference between lightning and the lightning bug”? Demonstrate your answer by providing an example from your own life when “almost the right word” created confusion, misunderstanding, or adversity.
2. How can knowing your fellow students and fostering a sense of community benefit your educational experience?
3. Part of effective communication involves knowing how to respond rather than react to something someone has said or written. In the online classroom format, why is it important to read a classmate’s post and assess that person’s intended message before you offer a response? How can this skill of responding help you in your career?

Sample Student DQ Response Format

What did Mark Twain mean when he said, “the difference between the right word and the almost right word is the difference between lightning and the lightning bug”? Demonstrate your answer by providing an example from your own life when “almost the right word” created confusion, misunderstanding, or adversity.

It is very important to use the right words when communicating. If you do not select your words carefully you can end up not getting your point across or miss a great opportunity. Using the right word makes sure you are understood correctly. If you are not careful about the words you use, it is easier for people to misinterpret them. This can have a negative impact in the medical field, as miscommunication affects “patients’ quality of care, health outcomes, adherence to treatment and satisfaction” and is also cited as the “most common reason for patient medical complaints” (Morgan, 2013, p. 123) The Discussion Of Osteoarthritis And Rheumatoid Arthritis .

I have experienced what the difference between the “right word” and the “almost right word” can do. A couple years ago I was having a tough time. I was really busy with a lot of different things and my family could tell it was wearing me down. One day my daughter came up and handed me a picture she drew of the two of us. I was in the middle of something and just took it and said, “Oh, that’s nice, thanks.” Later, I could see she was sad. I felt terrible and thought about how much work she put into the picture for me, and how she was trying so hard to make me happy. I used almost the right words, but not the right words. We both felt much better after I took the time to express how I really felt.

Reference:

Morgan, S. (2013). Miscommunication between patients and general practitioners: Implications
for clinical practice. Journal of Primary Health Care, 5(2), 123-128 The Discussion Of Osteoarthritis And Rheumatoid Arthritis .